ME cfw was very glitchy for me so I would rather recommend downgrading (which I've done 4 times (6.60>6.20, 6.39>6.35, 6,35>6.20)) on both a 2000 and 3000 and I (and nobody else) has ever posted that it bricked, uninstalling ME CFW means modifying vshmain.prx (VERY RISKY), so downgrade then upgrade (and for next time i would recommend PRO CFW)
downgrader link:
6.60 Downgrader Released, PSP Hacks - PSP Slim Hacks


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